Convalescent plasma therapy has a mixed history of success, but doctors are willing to try amid efforts against the pandemic.
In New York and Houston, pints of straw-colored convalescent plasma have dripped into the veins of five U.S. coronavirus patients. Hundreds more there and across the nation are set to follow.
Plasma is the almost clear liquid that remains after red and white blood cells and platelets are removed from blood. It contains antibodies that can fight disease. "The world is downloading it," said Arturo Casadevall, one of the project's organizers and chairman of molecular microbiology and immunology at Johns Hopkins Bloomberg School of Public Health.
In both studies, almost all the patients also received antiviral and other treatments, making it difficult to know in a group of only 15 patients what specifically helped. Speedy science: From a published paper to reality in less than three weeksThe idea of giving desperately ill patients blood plasma from people who recovered from the same illness is more than a century old and was first used to treat a German child suffering from diphtheria.
When a person is infected with COVID-19, the body creates blood proteins called antibodies to attack the virus, said Mark Slifka, a viral immunologist at the Oregon Health and Science University in Portland. People who tested positive for COVID-19 and fully recovered can register on the Plasma Project's website to see whether they are eligible and if there's a plasma donation program near them.
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