The newly-discovered neuromarker could prove to be a potent tool for treating substance abuse.
The discovery could help to better understand craving disorders, develop new treatments, and also improve methods for diagnosing substance use disorders. Physicians diagnose a lot of diseases today by identifying biological markers in a patient — diabetes, for example, is diagnosed by testing for a blood marker called A1C.
Kober and her colleagues set out to determine whether they could find an equivalent marker for craving. They decided to use a machine learning algorithm to analyze brain activity. To be precise, they set out to test the hypothesis that people experiencing cravings might share a pattern of brain activity. If that were to be the case, a
The newly-observed pattern — dubbed "Neurobiological Craving Signature " — includes activity in brain areas that have previously been linked to addiction. The new pattern works for many different substances, according to the scientists. "It’s really a biomarker for craving and addiction," Kober explained. "There’s something common across all of these substance use disorders that is captured in a moment of craving.”
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