Scientists used the groundbreaking CRISPR technique to create the lizards.
Scientists have genetically modified reptiles for the first time, to create tiny mutant albino lizards., or brown anole lizard, which is around the size of an index finger. Of the eggs used in the study, between 6 to 9 percent of themj were born with the gene-edited traits.
To get around this problem, the researchers took advantage of the transparent membrane covering the lizard's ovary. This enabled them to predict which eggs were next in line to be fertilized, and use CRISPR on unfertilized eggs. "We had to wait three months for the lizards to hatch, so it's a bit like slow-motion gene editing," Menke said. Using the term allele, a variant form of a gene, he explained:"But it turns out that when we did this procedure, about half of the mutant lizards that we generated had gene-editing events on the maternal allele and the paternal allele."
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