Tripping Through Time: How Psychedelic Drugs Reopen the Brain’s Learning Window — Johns Hopkins Medicine res |
Johns Hopkins Medicine researchers found that psychedelic drugs can reopen “critical periods” in the brain, enhancing its receptivity to learning from the environment.
Critical periods have been demonstrated to perform such functions as helping birds learn to sing and helping humans learn a new language, relearn motor skills after a stroke, and establish dominance of one eye over the other eye. MDMA, a psychedelic drug that arouses feelings of love and sociability, opens a critical period in miceAt the time, Dölen thought MDMA’s prosocial properties smooth the way for opening the critical period, but her team was surprised, she says, to find in the current study that other psychedelic drugs without prosocial properties could also reopen critical periods.
For mice given ketamine, the critical period of social reward learning stayed open in the mice for 48 hours. With, the open state lasted two weeks. For mice given MDMA, LSD and ibogaine, the critical period remained open for two, three and four weeks, respectively.
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