A 1-week schedule of 30 Gy delivered in five daily fractions was safe and effective in patients with early breastcancer, preprint reveals. OncTwitter
, a 1-week schedule of partial breast radiation — 30 Gy delivered in 5 daily fractions — is safe, effective, and convenient for both patients and hospitals.According to numerous guidelines, partial breast irradiation after lumpectomy is a sound approach for early-stage breast cancer, but there is a lack of consensus about treatment schedules.
Half of patients had left-sided tumors, 94.5% had invasive ductal carcinomas, 96.6% had grade 1 or grade 2 disease, and tumors were luminal-like in 99.2% of patients. Ten patients had grade 2 late toxicities, including edema, asthenia, and fibrosis; there were no grade 3 or higher adverse events. The safety and efficacy outcomes are in line with previous reports, including those that used different dosage and/or fractionation schedules.Quality of life was not assessed.Disclosures
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