Why Is PCOS Still So Hard for Doctors to Understand?

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Why Is PCOS Still So Hard for Doctors to Understand?
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You and your doctor are not alone in pinpointing exactly what PCOS is.

Some of the most familiar markers of PCOS can happen as the result of extra androgens, though it’s not clear if the excess androgens are an actual cause of PCOS or just a symptom of another potential cause . It’s probably pretty easy for you to see how extra testosterone could translate into something like more face and body hair, but you might find it harder to pin down how this would relate to irregular ovulation. Well, you’re in great company, because doctors aren’t too sure, either.

Genetics could also be a factor in PCOS development. PCOS tends to cluster in families, which some experts believe may point to a strong genetic link, Redman says. Whether someone develops PCOS could be the result of aResearchers have begun to unravel the genetic origins of this disorder through DNA samples. A 2019 meta-analysis of 261 people inrevealed that a gene called DENND1A could have a role in the development of PCOS in white families of Eurpean heritage.

Additionally, some experts believe fetuses that are exposed to unusually high testosterone levels while in the womb , Redman says. The excess testosterone could influence the genetic material of the fetus, including any eventual eggs and ovaries it develops. This seems to set up these individuals for developing PCOS later on, though some research suggests the deciding factor could be

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