Win-win in muscle research: Faster results and fewer laboratory animals thanks to new method

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Win-win in muscle research: Faster results and fewer laboratory animals thanks to new method
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To study muscle diseases, scientists rely on the mouse as a model organism. Researchers have now developed a new method that is not only faster and more efficient than conventional ones but also greatly reduces the number of experimental animals needed for studying the function of genes in muscle fibers.

A pharmaceutical product called TT-10, which spurs proliferation of heart muscle cells, was thought to offer promise to treat heart attacks. In a mouse heart-attack model several years ago, ...

Almost one in five people lacks the protein alpha-actinin-3 in their muscle fiber. Researchers now show that more of the skeletal muscle of these individuals comprises slow-twitch muscle fibers, ... A single protein is a master regulator of mouse muscle function during aging, a new study finds. Blocking this protein increased muscle strength and endurance in old animals. It may play a role in ...

Researchers building a model of muscle damage in a cultured system found that components leaking from broken muscle fibers activate ''satellite cells,'' which are muscle stem ...

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