The unvaccinated or people with weak immune systems at high risk of severe disease can receive an injection if exposed to an infected person.
severe disease, hospitalization and death. But use of the drugs has remained limited because they typically must be administered through an IV infusion and need to be given within 10 days after Covid symptoms begin.The first dose needs to be administeredThe FDA's expanded authorization was based on the results of a large clinical trial of the Regeneron cocktail, which contains the monoclonal antibodies casirivimab and imdevimab.
Of the 204 participants who were infected with the coronavirus but were symptom-free when they entered the study, the antibody injection reduced their risk of developing Covid symptoms by 32 percent over the next four weeks. There were only a few immunocompromised people in the study. Nevertheless, the FDA has identified members of this demographic as candidates for the preventive treatment. Others include people at high risk of exposure to infected individuals at work or in nursing homes or prisons. People who are expected to have ongoing exposure to the virus from close contacts can receive repeated doses of the antibody cocktail on a monthly basis.
According to the FDA authorization, individuals must be unvaccinated or immunocompromised, at high risk of severe Covid, and must have been in close contact with someone who has tested positive to receive the preventive treatment.
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