For eons, deoxyribonucleic acid (DNA) has served as a sort of instruction manual for life, providing not just templates for a vast array of chemical structures but a means of managing their production.
– there are various approaches that can be taken. Here, scientists wanted to build something that was more adaptable than previous efforts, with a broader range of potential uses.
"Programmability and scalability constitute two critical factors in achieving general-purpose computing," the researchers"Programmability enables specification of the device to perform various algorithms whereas scalability allows the handling of a growing amount of work by the addition of resources to the system.", or DPGAs: short segments of DNA fixed together to create larger structures, that could then be built into integrated circuits of various combinations.
These DPGAs were made by mixing DNA strands with buffer fluid in test tubes, relying on chemical reactions to make the attachments, and the combinations required to build the DICs that the researchers were aiming for. Some detailed modeling was required too, in order to figure out how to manage input and output signals, and execute
, just like a standard computer. Larger circuits too big for a single DPGA were broken down into component parts for building.
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