San Diego's Fate Therapeutics lays off 315 employees — more than half of its workforce

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San Diego's Fate Therapeutics lays off 315 employees — more than half of its workforce
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In addition to job cuts, Fate Therapeutics ends a major collaboration with a Johnson & Johnson company and scales back its development pipeline of immunotherapies.

Fate Therapeutics, a San Diego-based biopharmaceutical company, is laying off more than half of its workforce and ending a key collaboration agreement with Janssen Biotech.

Fate is cutting 315 positions across its three locations in San Diego and a San Francisco facility, according to a WARN notice filed with the state. The layoffs hit all parts of the business from the chief technical officer to research and development positions and human resources. After the first quarter ends in March, the company said it will have 220 employees.

The publicly traded company was founded in 2007 and develops cell therapies to treat cancer and immune disorders. Fate is a clinical-stage company that works in the realm of immunotherapies.Some of these therapies, such as natural killer cell programs, focus on equipping a patient’s own immune system to identify and destroy infected cells. Another avenue is CAR-T therapies, which genetically modify immune cells to fight a certain cancer and integrate those fighter cells into the patient.

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