Researchers at The University of Queensland have found an anti-aging function in a protein deep within human cells. Associate Professor Steven Zuryn and Dr. Michael Dai at the Queensland Brain Institute have discovered that a protein called ATSF-1 controls a fine balance between the creation of n
University of Queensland researchers discovered that the protein ATFS-1 aids in cell longevity by balancing new mitochondria creation and repair. This finding could impact our understanding of aging and diseases like dementia and Parkinson’s.
Associate Professor Steven Zuryn and Dr. Michael Dai at the Queensland Brain Institute have discovered that a protein called ATSF-1 controls a fine balance between the creation of new mitochondria and the repair of damaged mitochondria., produce energy within cells to power biological functions but the toxic by-products of this process contribute to the rate at which the cell ages.
A live C. elegans animal with mitochondria in its nervous system decorated with red and green fluorescent proteins. Credit: The authors“We studied ATFS-1 in C. elegans, or roundworms, and saw that enhancing its function promoted cellular health, meaning the worms became more agile for longer.“Mitochondrial dysfunction lies at the core of many human diseases, including common age-related diseases such as dementia and Parkinson’s.
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