Why is the coronavirus so much more deadly for men than for women?

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Why is the coronavirus so much more deadly for men than for women?
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An analysis of all COVID-19 patient profile studies filed in China from December 2019 to February 2020 suggests that men account for roughly 60% of those who are infected and become sick

If you’ve been infected with the coronavirus, the chances that you will become critically ill depend on many factors.

In China, where cigarette smoking rates are among the highest in the world, 54% of men were current smokers in 2010, and 8.4% were ex-smokers. Yet only 3.4% of Chinese women had ever smoked, according to the same 2016 study. At the same time, the death rates of infected female mice shot up when their ovaries were removed, or when they got drugs that suppressed the activity of the hormoneTo Perlman, those dual findings strongly suggest that there’s something about estrogen that protects against the ravages of deadly coronaviruses — and he suspects it’s true for the new SARS-CoV-19 virus as well.

But Pinkerton and others suggest that humans’ responses to COVID-19 could reveal important distinctions between the way that men’s and women’s immune systems fight infection. They suspect that hormonal differences may be playing a key role in that immune response.

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